Human CXCL5 Protein (CXL-HM205)

Express System: HEK293
Product Tag: N-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Ala37-Asn114

Catalog #CXL-HM205

Price

$345⁰⁰

Size

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Human CXCL5 Protein (CXL-HM205) Summary

Product Description

Recombinant Human CXCL5 Protein is expressed from HEK293 with hFc (IgG1) tag at the N-terminus.It contains Ala37-Asn114.

Product Background

C-X-C motif chemokine ligand 5 (CXCL5), also known as epithelial neutrophil-activating peptide 78 (ENA-78), is a pivotal member of the ELR+ CXC chemokine family, characterized by a conserved glutamic acid-leucine-arginine motif. CXCL5 plays a central regulatory role in shaping the tumor immune microenvironment (TIME). Its expression is regulated by transcription factors (NF-κB, STAT3, SP1, p53), epigenetic modifications (DNA methylation, histone acetylation, microRNAs), and cytokines/growth factors (IL-1β, TNF, EGF).

Human CXCL5 Protein (CXL-HM205) Specifications/Details

Protein	CXCL5
Synonyms	ENA78; SCYB5; ENA-78(1-78);;ENA78(1-78)
Accession	P42830
Species	Human
Biotinylated	no
Amino Acid Range	Ala37-Asn114
Molecular Weight	The protein has a predicted MW of 34.30 kDa. Due to glycosylation, the protein migrates to 35-45 kDa based on Bis-Tris PAGE result.
Product Tag	N-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human CXCL5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human CXCL5 is greater than 95% as determined by SEC-HPLC.