- Express System: HEK293
- Purity: > 95% as determined by HPLC
- Activity: Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test).
- Recomended Products: VLP Control (VLP-HM00C)
- Amino Acid Range: Met1-Phe372
Human CXCR5 VLP (CXC-HM1R5) Summary
Product Description |
Recombinant Human CXCR5 VLP is expressed from HEK293.It contains Met1-Phe372 (It may have cross reaction with anti-His antibody). |
Product Background |
CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP |
Human CXCR5 VLP (CXC-HM1R5) Specifications/Details
Protein |
CXCR5 |
Synonyms |
CXC-R5; CXCR-5; MDR-15; MDR15; CD185; BLR1 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Phe372 |
Molecular Weight |
The protein has a predicted MW of 54.90 kDa. |
Activity |
Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test). |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Other Available Proteins:
Finding available proteins...
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