Human CXCR5 VLP (CXC-HM1R5)
  • Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test). See testing image for detail.
  • Amino Acid Range: Met1-Phe372
Catalog #CXC-HM1R5
Regular price $1,235.00
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Human CXCR5 VLP (CXC-HM1R5) Summary

Product Description

Recombinant Human CXCR5 VLP is expressed from HEK293.It contains Met1-Phe372 (It may have cross reaction with anti-His antibody).

Product Background

CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it.

Product Category

Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Human CXCR5 VLP (CXC-HM1R5) Specifications/Details

Protein
CXCR5
Synonyms
CXC-R5; CXCR-5; MDR-15; MDR15; CD185; BLR1
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Met1-Phe372
Molecular Weight
The protein has a predicted MW of 54.90 kDa.
Activity
Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test). See testing image for detail.
Expression System
HEK293
Purity
> 95% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.
Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in PBS, 150mM L-Arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test). Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test).
The purity of Human CXCR5 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human CXCR5 VLP is greater than 95% as determined by SEC-HPLC.
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