• Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test).
  • Negative Control: VLP Control (VLP-HM00C)
  • Amino Acid Range: Met1-Phe372
Catalog #CXC-HM1R5
Price
Regular price $1,21000
Regular price Sale price $1,21000
/
Size
Avantor VWR Fisher Scientific

Order by 4pm ET for delivery on:

Human CXCR5 VLP (CXC-HM1R5) Summary

Product Description

 Recombinant Human CXCR5 VLP is expressed from HEK293.It contains Met1-Phe372 (It may have cross reaction with anti-His antibody).

Product Background

 CXCR5 is a serpentine receptor implicated in cell migration in lymphocytes and differentiation in leukocytes. It causes MAPK pathway activation and has known membrane partners for signaling. CXCR5 is also expressed in HL-60 cells, a human acute myeloid leukemia line, following treatment with all-trans retinoic acid, which induces differentiation toward a neutrophil-like state. CXCR5 is necessary for this process; differentiation was crippled in CXCR5 knockout cells and enhanced in cells ectopically expressing it.

Human CXCR5 VLP (CXC-HM1R5) Specifications/Details

Protein
 CXCR5
Synonyms
 CXC-R5; CXCR-5; MDR-15; MDR15; CD185; BLR1;CXCR5
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Phe372
Molecular Weight
 The protein has a predicted MW of 54.90 kDa.
Activity
 Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test).
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test). Immobilized Human CXCR5 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-CXCR5 Antibody, hFc Tag with the EC50 of 71.7ng/ml determined by ELISA (QC Test).
The purity of Human CXCR5 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human CXCR5 VLP is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...