Sensorgram showing the binding kinetics of different ligand concentrations over time. The x-axis represents time in seconds, and the y-axis shows response units (RU). Multiple curves, each representing a different concentration, show the ligand-receptor interaction and dissociation.
Human TRAIL R3/DcR1 Protein (TRA-HM103)
Sensorgram showing the binding kinetics of different ligand concentrations over time. The x-axis represents time in seconds, and the y-axis shows response units (RU). Multiple curves, each representing a different concentration, show the ligand-receptor interaction and dissociation.
Human TRAIL R3/DcR1 Protein (TRA-HM103)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Tyr24-Ala236
Catalog #TRA-HM103
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Size
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Human TRAIL R3/DcR1 Protein (TRA-HM103) Summary

Product Description

 Recombinant Human TRAIL R3/DcR1 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Tyr24-Ala236.

Product Background

 The tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) is a member of the TNF family, which mediates apoptosis by the extrinsic pathway. Up-regulation of decoy receptors, DcR1 and DcR2, may result in diminished binding of TRAIL to their functional receptors. DcR1 expression occurs in a subset of EC and may contribute to resistance to TRAIL-induced apoptosis.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human TRAIL R3/DcR1 Protein (TRA-HM103) Specifications/Details

Protein
 TRAIL R3/DcR1
Synonyms
 CD263; DCR1; DCR1-TNFR; LIT; TRAIL-R3; TRAILR3; TRID; TNFRSF10C
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Tyr24-Ala236
Molecular Weight
 The protein has a predicted MW of 23.5 kDa. Due to glycosylation, the protein migrates to 60-80 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human TRAIL R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human TRAIL R3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human TRAIL R3 is greater than 95% as determined by SEC-HPLC. The purity of Human TRAIL R3 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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