Name: Human DDR1 Protein (DDR-HM2R1)
Brand: KactusBio
SKU: DDR-HM2R1-100UG
Price: 330.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human DDR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-DDR1 Antibody, hFc Tag with the EC50 of 13.6ng/ml determined by ELISA.
Amino Acid Range: Asp21-Ala417

Catalog #DDR-HM2R1

Size

100UG

500UG

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Human DDR1 Protein (DDR-HM2R1) Summary

Product Description	Recombinant Human DDR1 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Asp21-Ala417.
Product Background	Discoidin domain receptor1 (DDR1) is a collagen activated receptor tyrosine kinase and an attractive anti-fibrotic target. Its expression is mainly limited to epithelial cells located in several organs including skin, kidney, liver and lung. DDR1's biology is elusive, with unknown downstream activation pathways; however, it may act as a mediator of the stromal-epithelial interaction, potentially controlling the activation state of the resident quiescent fibroblasts.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human DDR1 Protein (DDR-HM2R1) Specifications/Details

Protein	DDR1
Synonyms	HGK2; MCK-10; CAK; EDDR1; NEP; NTRK4; PTK3A; RTK6; TRKE; CD167a; EC 2.7.10.1
Accession	Q08345-1
Species	Human
Biotinylated	no
Amino Acid Range	Asp21-Ala417
Molecular Weight	The protein has a predicted MW of 69.97 kDa. Due to glycosylation, the protein migrates to 80-100 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human DDR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-DDR1 Antibody, hFc Tag with the EC50 of 13.6ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human DDR1, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-DDR1 Antibody, hFc Tag with the EC50 of 13.6ng/ml determined by ELISA.
	Human DDR1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human DDR1 is greater than 90% as determined by SEC-HPLC.

Other Available Proteins:

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