Name: Human DLL3 Protein (DLL-HM203)
Brand: KactusBio
SKU: DLL-HM203-100UG
Price: 495.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human DLL3, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala27-Arg490

Catalog #DLL-HM203

Size

100UG

500UG

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Product Description	Recombinant Human DLL3 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Ala27-Arg490.
Product Background	Delta-like protein 3 (DLL3) is a transmembrane protein that belongs to the Delta/Serrate/Lag-2 (DSL) family of Notch ligands. DLL3 inhibits primary neurogenesis and may be required to divert neurons along a specific differentiation pathway. It plays a role in the formation of somite boundaries during segmentation of the paraxial mesoderm.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Protein	DLL3
Synonyms	Delta3; DLL3; Pudgy; SCDO1; SCDO1delta3
Accession	Q9NYJ7-1
Species	Human
Biotinylated	no
Amino Acid Range	Ala27-Arg490
Molecular Weight	The protein has a predicted MW of 74.19 kDa. Due to glycosylation, the protein migrates to 75-85 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human DLL3, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human DLL3, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-DLL3 Antibody, hFc Tag with the EC50 of 2.8ng/ml determined by ELISA.
	Human DLL3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Biotinylated Anti-DLL3 Antibody, hFc Tag on Streptavidin-Biosensor can bind Human DLL3, hFc Tag with an affinity constant of 1.60 nM as determined in BLI assay (Gator® Prime).