Human EDA2R Protein (EDA-HM22R) Summary
Product Description |
Recombinant Human EDA2R Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Met1-Thr138. |
Product Background |
The X-linked ectodermal dysplasia receptor (XEDAR; also known as EDA2R or TNFRSF27) is a member of the TNFR superfamily that is highly expressed in ectodermal derivatives during embryonic development and binds to ectodysplasin-A2 (EDA-A2), a member of the TNF family that is encoded by the anhidrotic ectodermal dysplasia (EDA) gene. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human EDA2R Protein (EDA-HM22R) Specifications/Details
Protein |
EDA2R |
Synonyms |
X-linked ectodysplasin-A2 receptor; EDA-A2 receptor; EDA-A2; Tnfrsf27; Xedar |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Thr138 |
Molecular Weight |
The protein has a predicted MW of 42.08 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc (IgG1) |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human EDA2R on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human EDA2R is greater than 95% as determined by SEC-HPLC. |
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