Product Description |
Recombinant Human EMMPRIN/CD147 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala22-His205. |
Product Background |
CD147, also known as extracellular matrix metalloproteinase inducer (EMMPRIN) or basigin, is expressed in a variety of cell types. It is involved in the regulation of extracellular matrix (ECM) remodeling during physiological and pathological processes including wound healing, inflammatory diseases, and cancer. CD147 is a diagnostic and therapeutic target in cancer and inflammatory diseases, either directly or indirectly, by targeting CD147 partners. |
Product Category |
Recombinant Protein |
Protein |
EMMPRIN/CD147 |
Synonyms |
Basigin; BSG; CD147; 5F7; M6; OK; TCSF |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala22-His205 |
Molecular Weight |
The protein has a predicted MW of 21.2 kDa. Due to glycosylation, the protein migrates to 28-40 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human EMMPRIN, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-EMMPRIN Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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|
Immobilized Human EMMPRIN, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-EMMPRIN Antibody, hFc Tag with the EC50 of 3.0ng/ml determined by ELISA (QC Test). |
|
|
Human EMMPRIN on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
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The purity of Human EMMPRIN is greater than 95% as determined by SEC-HPLC. |
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