Human ENPP-2/Autotaxin Protein (ENP-HM101)
Catalog: ENP-HM101
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| Product Description | Recombinant Human ENPP-2/Autotaxin Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Asp49-Ile863. |
Product Background |
Ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) also known as Autotaxin, is a secreted lysophospholipase D, which hydrolyzes lysophosphatidylcholine (LPC) into Lysophosphatidic acid (LPA). ENPP2 is an essential protein for normal development and its altered expression is associated with various human diseases. |
Product Category |
Recombinant Protein |
Target |
ENPP-2/Autotaxin |
| Synonyms | PDNP2; ATX-X; NPP2; PD-IALPHA; ENPP-2; E-NPP 2; Autotaxin; LysoPLD; ATX |
Gene/Protein ID |
NP_001035181 |
Species |
Human |
Exact Sequence |
Asp49-Ile863 |
| Molecular Weight | The protein has a predicted MW of 94.8 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result. |
Product Tag |
N-His |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Lyophilized |
| Shipping | Shipped at ambient temperature. |
| Formulation | Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
| Reconstitution | Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
| Stability And Storage | Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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Measured by its ability to cleave Bis (p-Nitrophenyl) Phosphate (BPNPP). The specific activity is > 10000 pmol/min/ug, as measured under the described conditions. |
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The purity of Human ENPP-2 is greater than 95% as determined by SEC-HPLC. |
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Human ENPP-2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%. |
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