Product Description |
Recombinant Human ENPP-2/Autotaxin Protein is expressed from HEK293 with His tag at the N-Terminus.It contains Asp49-Ile863. |
Product Background |
Ectonucleotide pyrophosphatase/phosphodiesterase 2 (ENPP2) also known as Autotaxin, is a secreted lysophospholipase D, which hydrolyzes lysophosphatidylcholine (LPC) into Lysophosphatidic acid (LPA). ENPP2 is an essential protein for normal development and its altered expression is associated with various human diseases. |
Product Category |
Recombinant Protein |
Target |
ENPP-2/Autotaxin |
Synonyms |
PDNP2; ATX-X; NPP2; PD-IALPHA; ENPP-2; E-NPP 2; Autotaxin; LysoPLD; ATX |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asp49-Ile863 |
Molecular Weight |
The protein has a predicted MW of 94.8 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human ENPP-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human ENPP-2 is greater than 95% as determined by SEC-HPLC. |
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