Human EPHA10 Protein (EPH-HM110)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human EPHA10, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus EFNA3, hFc Tag with the EC50 of 0.24ug/ml determined by ELISA. See testing image for detail.
Exact Sequence: Glu34-Ala565

Catalog: EPH-HM110

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Human EPHA10 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu34-Ala565.
Product Background	EphA10 (erythropoietin-producing hepatocellular carcinoma receptor A10) is a catalytically defective receptor protein tyrosine kinase in the ephrin receptor family.EphA10 was elevated and higher in tumor tissues than in normal tissues in some cancer types, including pancreatic cancer.EphA10 silencing reduced the proliferation, migration, and adhesion of MIA PaCa-2 and AsPC-1 pancreatic cancer cells. EphA10 plays a pivotal role in the tumorigenesis of pancreatic epithelial cells and is a novel therapeutic target for pancreatic cancer.
Product Category	Recombinant Protein

Target	EPHA10
Synonyms	EphA10; FLJ16103; FLJ33655; MGC43817
Gene/Protein ID	Q5JZY3-1
Species	Human
Exact Sequence	Glu34-Ala565
Molecular Weight	The protein has a predicted MW of 58.8 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human EPHA10, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus EFNA3, hFc Tag with the EC50 of 0.24ug/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human EPHA10, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human/Cynomolgus EFNA3, hFc Tag with the EC50 of 0.24ug/ml determined by ELISA.
	The purity of Human EPHA10 is greater than 95% as determined by SEC-HPLC.
	Human EPHA10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.