Name: Human EPHA3 Protein (EPH-HM1A3)
Brand: KactusBio
SKU: EPH-HM1A3-100UG
Price: 297.0 USD
Availability: InStock

Catalog #EPH-HM1A3

Size

100UG

500UG

Order by 4pm ET for delivery on:

Human EPHA3 Protein (EPH-HM1A3) Summary

Product Description	Recombinant Human EPHA3 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu21-Gln541.
Product Background	Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (‑295~‑261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human EPHA3 Protein (EPH-HM1A3) Specifications/Details

Protein	EPHA3
Synonyms	EK4; HEK; ETK; ETK1; EPHA3; TYRO4; HEK4
Accession	P29320-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu21-Gln541
Molecular Weight	The protein has a predicted MW of 59.9 kDa. Due to glycosylation, the protein migrates to 70-75 kDa based on Bis-Tris PAGE result.
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human EPHA3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human EPHA3 is greater than 95% as determined by SEC-HPLC.