Product Description |
Recombinant Human EphB4 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu16-Ala539. |
Product Background |
The erythropoietin-producing hepatocellular carcinoma (Eph) receptors are the largest family of receptor tyrosine kinases (RTKs) that include two major subclasses, EphA and EphB. They form an important cell communication system with critical and diverse roles in a variety of biological processes during embryonic development. The emerging picture suggests that EphB4 is a valuable and attractive therapeutic target for upper aerodigestive malignancies. |
Product Category |
Recombinant Protein |
Target |
EphB4 |
Synonyms |
EPHB4; HTK; MYK1; TYRO11 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu16-Ala539 |
Molecular Weight |
The protein has a predicted MW of 58.2 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human EphB4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human EphB4 is greater than 95% as determined by SEC-HPLC. |
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