Product Description |
Recombinant Human Fc gamma RIIIA/CD16a (V176) Domain 2 Protein is expressed from HEK293 with mFc tag at the C-terminus.It contains Gly107-Thr189. |
Product Background |
Human Fc gamma RIIIA/CD16a Protein is a receptor for the Fc region of IgG. Binds complexed or aggregated IgG and also monomeric IgG. Mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. |
Product Category |
Recombinant Protein |
Target |
Fc gamma RIIIA/CD16a (V176) Domain 2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly107-Thr189 |
Molecular Weight |
The protein has a predicted MW of 35.29 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-mFc |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human Fc gamma RIIIA (V176) Domain 2 Protein on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human Fc gamma RIIIA (V176) Domain 2 Protein is greater than 95% as determined by SEC-HPLC. |
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