Name: Human Fc gamma RIIIB/CD16b (NA1) Protein (FCR-HM11B)
Brand: KactusBio
SKU: FCR-HM11B-100UG
Price: 240.0 USD
Availability: InStock

Human Fc gamma RIIIB/CD16b (NA1) Protein (FCR-HM11B)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: The affinity constant of 8.55 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Gly17-Ser200(NA1)

Catalog #FCR-HM11B

Size

100UG

500UG

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Product Description	Recombinant Human Fc gamma RIIIB/CD16b (NA1) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gly17-Ser200(NA1).
Product Background	Human Fc gamma RIIIB/CD16b Protein is a receptor for the Fc region of immunoglobulins gamma. Low affinity receptor. Binds complexed or aggregated IgG and also monomeric IgG. Contrary to III-A, is not capable to mediate antibody-dependent cytotoxicity and phagocytosis. May serve as a trap for immune complexes in the peripheral circulation which does not activate neutrophils.
Product Category	Recombinant Protein

Target	Fc gamma RIIIB/CD16b (NA1)
Synonyms	CD16; Fc gamma RIIIB; FCG3; FCGR3B; FcgRIIIB; FCRIIIB; IGFR3; CD16b (NA2); CD16B; FCG3B; FCG3; FCGR3; FCR-10
Accession	AAA35881.1
Species	Human
Biotinylated	no
Amino Acid Range	Gly17-Ser200(NA1)
Molecular Weight	The protein has a predicted MW of 22.52 kDa. Due to glycosylation, the protein migrates to 40-50 kDa based on Bis-Tris PAGE result.
Activity	The affinity constant of 8.55 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human Fc gamma RIIIB (NA1), His Tag captured on CM5 Chip via anti-his antibody can bind Rituximab with an affinity constant of 8.55 uM as determined in SPR assay (Biacore T200).
	Human Fc gamma RIIIB (NA1) on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Fc gamma RIIIB (NA1) is greater than 95% as determined by SEC-HPLC.

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