Human FcRH5/FcRL5 Domain Protein (FCR-HM20D) Summary
Product Description |
Recombinant Human FcRH5/FcRL5 Domain Protein is expressed from HEK293 with hFc (IgG1) tag at the N-terminus.It contains Val745-Thr850. |
Product Background |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Product Category |
Recombinant Protein / Antibody discovery / ADC targets |
Human FcRH5/FcRL5 Domain Protein (FCR-HM20D) Specifications/Details
Protein |
FcRH5/FcRL5 |
Synonyms |
FcR-like protein 5; FcRH5; FcRL5; BXMAS1; CD307; CD307e; IFGP5; IRTA2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Val745-Thr850 |
Molecular Weight |
The protein has a predicted MW of 36.62 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result. |
Product Tag |
N-hFc (IgG1) |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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