Name: Human FcRH5/FcRL5 Protein (FCR-HM101)
Brand: KactusBio
SKU: FCR-HM101-100UG
Price: 346.5 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human FcRH5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.4 ng/ml determined by ELISA (QC Test).
Amino Acid Range: Gln16-Gly851

Catalog #FCR-HM101

Size

100UG

500UG

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Human FcRH5/FcRL5 Protein (FCR-HM101) Summary

Product Description	Recombinant Human FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln16-Gly851.
Product Background	FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent.
Product Category	Recombinant Protein / Antibody discovery / ADC targets

Human FcRH5/FcRL5 Protein (FCR-HM101) Specifications/Details

Protein	FcRH5/FcRL5
Synonyms	FcR-like protein 5; FcRH5; FcRL5; BXMAS1; CD307; CD307e; IFGP5; IRTA2
Accession	Q96RD9-1
Species	Human
Biotinylated	no
Amino Acid Range	Gln16-Gly851
Molecular Weight	The protein has a predicted MW of 92.38 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human FcRH5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.4 ng/ml determined by ELISA (QC Test).
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human FcRH5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.4 ng/ml determined by ELISA (QC Test).
	Human FcRH5 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Anti-FcRH5 Antibody, hFc Tag on ProA-Biosensor can bind Human FcRH5, His Tag with an affinity constant of 8.91 nM as determined in BLI assay (Gator® Prime).
	The purity of Human FcRH5 is greater than 95% as determined by SEC-HPLC.