Product Description |
Recombinant Human FcRH5/FcRL5 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Gln16-Gly851. |
Product Background |
FcRH5 is a cell surface marker enriched on malignant plasma cells when compared to other hematologic malignancies and normal tissues. DFRF4539A is an anti-FcRH5 antibody-drug conjugated to monomethyl auristatin E (MMAE), a potent anti-mitotic agent. |
Product Category |
Recombinant Protein |
Target |
FcRH5/FcRL5 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln16-Gly851 |
Molecular Weight |
The protein has a predicted MW of 92.38 kDa. Due to glycosylation, the protein migrates to 120-140 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human FcRH5, His Tag at 1 ug/ml (100 ul/well) on the plate. Dose response curve for Anti-FcRH5 Antibody, hFc Tag with the EC50 of 5.4 ng/ml determined by ELISA (QC Test). See testing image for detail. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
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