Human FcRH6 /FCRL6 Protein (FCR-HM206) Summary
Product Description |
Recombinant Human FcRH6 /FCRL6 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Leu20-Trp307. |
Product Background |
A surprising number of Fc receptor (FcR) relatives have been recognized recently with the potential capacity to modulate innate and adaptive immune responses. The six human FcR homologs (FcRH1-6), which belong to a phylogenetically conserved gene family, have variable numbers of extracellular immunoglobulin domains of five different subtypes. All but one of these new receptors, FcRH6, are expressed on B cells at different stages in differentiation. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human FcRH6 /FCRL6 Protein (FCR-HM206) Specifications/Details
Protein |
FcRH6/FCRL6 |
Synonyms |
FcR-like protein 6; FcRL6; FcRH6; IFGP6; Fc receptor-like 6; FLJ16056 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Leu20-Trp307 |
Molecular Weight |
The protein has a predicted MW of 58.4 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-hFc |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human FcRH6 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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