• Express System: HEK293
  • Product Tag: C-hFc (IgG1)
  • Purity: > 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
  • Activity: Immobilized Human FCRL2, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 89.4ng/ml determined by ELISA.
  • Amino Acid Range: Leu20-Val401
Catalog #FCR-HM202
Price
Regular price $34500
Regular price Sale price $34500
/
Size
Avantor VWR Fisher Scientific

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Human FcRL2/IRTA4 Protein (FCR-HM202) Summary

Product Description

Recombinant Human FcRL2/IRTA4 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Leu20-Val401.

Product Background

Fc receptor-like 2 (FCRL2) is highly expressed on B-cell chronic lymphocytic leukemia (B-CLL) cells and could possibly influence disease pathogenesis. FCRL2 mRNA expression was found to be expressed at considerably higher levels in peripheral blood mononuclear cells (PBMC) of B-CLL patients compared to controls (range 1.35- to 210-fold upregulation; P < 0.0001) and cells of other hematological diseases.

Human FcRL2/IRTA4 Protein (FCR-HM202) Specifications/Details

Protein
FcRL2/IRTA4
Synonyms
FcR-like protein 2; FcRL2; FCRH2; IFGP4; IRTA4; FCRL2; CD307b; FCRH2SPAP1B; IRTA4SPAP1C; SPAP1; SPAP1A
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Leu20-Val401
Molecular Weight
The protein has a predicted MW of 67.58 kDa. Due to glycosylation, the protein migrates to 85-105 kDa based on Bis-Tris PAGE result.
Activity
Immobilized Human FCRL2, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 89.4ng/ml determined by ELISA.
Product Tag
C-hFc (IgG1)
Fluorophore
Unconjugated
Expression System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin
Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human FCRL2, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 89.4ng/ml determined by ELISA. Immobilized Human FCRL2, hFc Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FCRL2 Antibody, hFc Tag with the EC50 of 89.4ng/ml determined by ELISA.
Human FcRL2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human FcRL2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human FcRL2 is greater than 90% as determined by SEC-HPLC. The purity of Human FcRL2 is greater than 90% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...