Product Description |
Recombinant Human FGF10 Protein is expressed from E.coli without tag.It contains Gln38-Ser208. |
Product Background |
Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease. |
Product Category |
Recombinant Protein |
Target |
FGF10 |
Synonyms |
FGF-10; KGF2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gln38-Ser208 |
Molecular Weight |
The protein has a predicted MW of 19.3 kDa. The protein migrates to 25 kDa based on Bis-Tris PAGE result. |
Activity |
The affinity constant of 8.43 nM as determined in SPR assay (Biacore T200). See testing image for detail. |
Product Tag |
No Tag |
Express System |
E.coli |
Purity |
> 90% as determined by Bis-Tris PAGE |
Endotoxin |
Less than 0.1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human FGF10, No Tag immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb), hFc Tag with an affinity constant of 8.43 nM as determined in SPR assay (Biacore T200). |
|
|
Human FGF10 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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