Human FGF10 Protein (FGF-HE010)

Express System: E.coli
Product Tag: No Tag
Purity: > 90% as determined by Tris-Bis PAGE
Activity: The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Exact Sequence: Gln38-Ser208

Catalog: FGF-HE010

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Product Description	Recombinant Human FGF10 Protein is expressed from E.coli without tag.It contains Gln38-Ser208.
Product Background	Fibroblast growth factor 10 (FGF10) regulates multiple stages of structural lung morphogenesis, cellular differentiation, and the response to injury. As a driver of lung airway branching morphogenesis, FGF10 signaling defects during development lead to neonatal lung disease. Lung diseases impact patients across the lifespan, from infants in the first minutes of life through the aged population. Congenital abnormalities of lung structure can cause lung disease at birth or make adults more susceptible to chronic disease.
Product Category	Recombinant Protein

Target	FGF10
Synonyms	FGF-10; KGF2
Gene/Protein ID	O15520
Species	Human
Exact Sequence	Gln38-Ser208
Molecular Weight	The protein has a predicted MW of 19.3 kDa. The protein migrates to 25 kDa based on Tris-Bis PAGE result.
Activity	The affinity constant of 0.299 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	No Tag
Express System	E.coli
Purity	> 90% as determined by Tris-Bis PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in 20mM Tris, 150mM NaCl (pH 8.0). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Human FGF10, No Tag immobilized on CM5 Chip can bind Human FGFR2 beta (IIIb) , hFc Tag with an affinity constant of 0.299 nM as determined in SPR assay (Biacore T200).
	Human FGF10 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.