Human FGFR2 alpha (IIIc) Protein (FGR-HM2CD)
Human FGFR2 alpha (IIIc) Protein (FGR-HM2CD)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Arg22-Glu377
Catalog #FGR-HM2CD
Regular price $345.00
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Product Description
Recombinant Human FGFR2 alpha (IIIc) Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Arg22-Glu377.
Product Background
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. A frequent splicing event involving FGF R1 and 2 results in receptors containing all three Ig domains, referred to as the alpha- isoform, or only IgII and IgIII, referred to as the beta- isoform.
Product Category
Recombinant Protein
Target
FGFR2 alpha (IIIc)
Synonyms
FGF R2a; FGFR2 alpha; KGFR; CD332; BBDS; BEK; BFR-1; CEK3; CFD1; ECT1; JWS; K-SAM; KGFR; TK14; TK25; FLJ98662
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Arg22-Glu377
Molecular Weight
The protein has a predicted MW of 40.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Product Tag
C-His
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human FGFR2 alpha (IIIc) on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
The purity of Human FGFR2 alpha (IIIc) is greater than 95% as determined by SEC-HPLC.

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