Human FGL1 Protein (FGL-HM211)
Catalog: FGL-HM211
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Product Description | Recombinant Human FGL1 Protein is expressed from HEK293 with hFc tag at the N-Terminus.It contains Asp64-Asn305. |
Product Background |
Fibrinogen-like protein 1 (FGL-1) is a protein that is structurally related to fibrinogen. In humans, FLG-1 is encoded by the FGL1 gene.Fibrinogen-like protein 1 is a member of the fibrinogen family of proteins, which also includes fibrinogen, fibrinogen-like protein 2, and clotting factors V, VIII, and XIII.Fibrinogen-like Protein 1 is a major immune inhibitory ligand of LAG-3. |
Product Category |
Recombinant Protein |
Target |
FGL1 |
Synonyms | FGL1; FGL-1; Hepassocin; HP-041; HFREP-1; LFIRE-1; HFREP1; Lag3 ligand |
Gene/Protein ID |
Q08830 |
Species |
Human |
Exact Sequence |
Asp64-Asn305 |
Molecular Weight | The protein has a predicted MW of 54.8 kDa. Due to glycosylation, the protein migrates to 60-66 kDa based on Tris-Bis PAGE result. |
Activity |
Immobilized Human LAG3, His Tag at 2ug/ml (100ul/Well) on the plate. Dose response curve for Human FGL1, hFc Tag with the EC50 of 0.91ug/ml determined by ELISA. See testing image for detail. |
Product Tag |
N-hFc |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 90% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22um filtered solution in 20mM PB, 250mM NaCl (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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