Human FOLR2 Protein (FOL-HM1R2)

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Activity: Immobilized Human FOLR2, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FOLR2 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Thr17-Met228

Catalog: FOL-HM1R2

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Product Description	Recombinant Human FOLR2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Thr17-Met228.
Product Background	FOLR1 and FOLR2 are equipped with cellular glycosylphosphatidylinositol (GPI) anchors. FOLR1 is secreted from epithelia with or without a micelle-encapsulated GPI-anchor into milk and other body fluids/secretions, e.g. semen where its interaction with spermatozoa indicates a role in male fertility. FOLR1 and FOLR2 serve as serum biomarkers of various diseases. FOLR3 possesses no GPI-anchor and originates from secretory granules of neutrophil granulocytes; its concentration in serum correlates to the FOLR3 content in leukocytes and rises with increased leukocyte counts (infection, malignancy and pregnancy).
Product Category	Recombinant Protein

Target	FOLR2
Synonyms	FBP；FOLR2；OLR2；BETA-HFR；FR-BETA；FR-P3
Gene/Protein ID	P14207
Species	Human
Exact Sequence	Thr17-Met228
Molecular Weight	The protein has a predicted MW of 25.5 kDa. Due to glycosylation, the protein migrates to 30-38 kDa based on Tris-Bis PAGE result.
Activity	Immobilized Human FOLR2, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FOLR2 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Express System	HEK293
Purity	> 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

	Immobilized Human FOLR2, His Tag at 0.2ug/ml (100ul/well) on the plate. Dose response curve for Anti-FOLR2 Antibody, hFc Tag with the EC50 of 4.1ng/ml determined by ELISA.
	The purity of Human FOLR2 is greater than 95% as determined by SEC-HPLC.
	Human FOLR2 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.