Name: Human Coagulation factor XI Protein (FXI-HM101)
Brand: KactusBio
SKU: FXI-HM101-100UG
Price: 379.5 USD
Availability: InStock

Human Coagulation factor XI Protein (FXI-HM101)

Immobilized Human Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA.

Human Coagulation factor XI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human Coagulation factor XI is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Glu19-Val625

Catalog #FXI-HM101

Size

100UG

500UG

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Product Description	Recombinant Human Coagulation factor XI Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu19-Val625.
Product Background	Coagulation factor (F)XI has been described as a component of the early phase of the contact pathway of blood coagulation, acting downstream of factor XII.In contrast to its mild hemostatic activities, FXI is known to play a significant role in thrombosis, as it is a demonstrated independent risk factor for deep vein thrombosis, ischemic stroke, and myocardial infarction. A better understanding of the varied and complex role of FXI in both thrombosis and hemostasis will help to allow better prediction of bleeding risk in FXI-deficient patients and also informing the development of targeted agents to inhibit the thrombotic activities of FXI while preserving hemostasis.
Product Category	Recombinant Protein / Antibody discovery

Protein	Coagulation factor XI
Synonyms	Coagulation factor XI; FXI; PTA; F11;
Accession	P03951-1
Species	Human
Biotinylated	no
Amino Acid Range	Glu19-Val625
Molecular Weight	The protein has a predicted MW of 69.1 kDa. Due to glycosylation, the protein migrates to 70-80 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 25mM HEPES, 150mM NaCl (pH 7.5). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Coagulation factor XI, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-Factor XI Antibody, hFc Tag with the EC50 of 7.4ng/ml determined by ELISA.
	Human Coagulation factor XI on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human Coagulation factor XI is greater than 95% as determined by SEC-HPLC.