Regular price
$495.00
Order by 4pm ET for delivery on:
Non-biotinylated Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402) Summary
Product Description |
Recombinant Human GARP&Latent TGF Beta 2 Complex Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus of GARP.It contains His20-Leu628(GARP) and Leu21-Ser414(Latent TGF Beta 2). |
Product Background |
GARP&Latent TGF Beta is a complex found on surface of many types of cells. In Tregs, GARP is involved in TCR-mediated activation of Latent TGF-β and thus promoting secretion and activation of TGF-β. Integrin αvβ8 on the surface of immune cells and other cells recognizes RGD in LAP, resulting in the release of mature TGF-β from the TGF-β&GARP complex. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery/Others |
Non-biotinylated Human GARP&Latent TGF Beta 2 Complex Protein (GAT-HM402) Specifications/Details
Protein |
GARP&Latent TGF Beta 2 Complex |
Synonyms |
Garpin; GARP; LRRC32; D11S833E; GARP&Latent TGF B; GARP&TGF B; Cetermin; G-TSF; LAP; TGF-beta-2; TGF Beta 2; GARP&Latent TGF Beta 2 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
His20-Leu628(GARP) & Leu21-Ser414(Latent TGF Beta 2) |
Molecular Weight |
The protein has a predicted MW of 70.3 kDa (GARP) and 45.53 kDa (Latent TGF Beta 2). Due to enzyme lysis and glycosylation, the protein migrates to 72-77 kDa (GARP), 13 kDa and 46-48 kDa (Latent TGF Beta 2) based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 0.1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking. |
Stability And Storage |
-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human GARP&Latent TGF Beta 2 Complex on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human GARP&Latent TGF Beta 2 Complex is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
