Name: Human GDF15 (H202D) Protein (GDF-HE116)
Brand: KactusBio
SKU: GDF-HE116-100UG
Price: 375.0 USD
Availability: InStock

Express System: E.coli
Product Tag: N-His
Purity: > 95% as determined by Bis-Tris PAGE
Activity: Immobilized Human GDF15 (H202D), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Ala197-Ile308 (H202D)

Catalog #GDF-HE116

Size

100UG

500UG

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Product Description	Recombinant Human GDF15 (H202D) Protein is expressed from E.coli with His tag at the N-terminus.It contains Ala197-Ile308 (H202D).
Product Background	Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GDF15, is dimerized, and is cleaved and secreted into the circulation as a mature dimer GDF15.
Product Category	Recombinant Protein / Antibody discovery

Protein	GDF15 (H202D)
Synonyms	GDF-15; MIC-1; NAG-1; PDF; PLAB; PTGFB; GDF15; MIC1; RG-1; Placental TGF-beta; PTGF-beta; PTGFBPTGF-beta; Placental TGF-β; PTGF-β; PTGFBPTGF-β
Accession	Q99988
Species	Human
Biotinylated	no
Amino Acid Range	Ala197-Ile308 (H202D)
Molecular Weight	The protein has a predicted MW of 13.36 kDa. The protein migrates to 15-16 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human GDF15 (H202D), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA. See testing image for detail.
Product Tag	N-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in 50mM HAc (pH 2.9). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in 50mM HAC (pH 2.9).
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GDF15 (H202D), His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human GFRAL, hFc Tag with the EC50 of 15.1ng/ml determined by ELISA.
	Human GDF15 (H202D) on Bis-Tris PAGE under reduced (R) condition and Non reducing (N) condition. The purity is greater than 95%.