Human GHR/Growth Hormone R Protein (GHR-HM101)
Human GHR/Growth Hormone R Protein (GHR-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala27-Tyr264
Catalog #GHR-HM101
Regular price $297.00
/
Size

Order now, ships by:

Product Description

Recombinant Human GHR/Growth Hormone R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Tyr264.

Product Background

Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.

Product Category

Recombinant Protein / Antibody discovery / Antibody discovery | Others

Protein

GHR/Growth Hormone R

Synonyms

GH receptor; GHBP; GHR; GHR/BP

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ala27-Tyr264

Molecular Weight

The protein has a predicted MW of 28.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1 EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human GHR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human GHR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human GHR is greater than 95% as determined by SEC-HPLC. The purity of Human GHR is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed