Human GHR/Growth Hormone R Protein (GHR-HM101)
Human GHR/Growth Hormone R Protein (GHR-HM101)
  • Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala27-Tyr264
Catalog #GHR-HM101
Regular price $270.00
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Product Description

Recombinant Human GHR/Growth Hormone R Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala27-Tyr264.

Product Background

Pegvisomant, a growth hormone receptor (GHR) antagonist, is a well-known drug that was designed to treat acromegaly. However, recent studies have indicated that the GHR is a "moonlighting" protein that may exhibit dual functions based on its localization in the plasma membrane and nucleus.

Product Category

Recombinant Protein / Antibody discovery

Protein

GHR/Growth Hormone R

Synonyms

GH receptor; GHBP; GHR; GHR/BP

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Ala27-Tyr264

Molecular Weight

The protein has a predicted MW of 28.8 kDa. Due to glycosylation, the protein migrates to 45-60 kDa based on Bis-Tris PAGE result.

Product Tag

C-His

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Human GHR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human GHR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human GHR is greater than 95% as determined by SEC-HPLC. The purity of Human GHR is greater than 95% as determined by SEC-HPLC.

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support@kactusbio.us

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