Human GITR/TNFRSF18 Protein (GTR-HM201)
Human GITR/TNFRSF18 Protein (GTR-HM201)
Human GITR/TNFRSF18 Protein (GTR-HM201)
Human GITR/TNFRSF18 Protein (GTR-HM201)
  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln26-Glu161
Catalog #GTR-HM201
Regular price $270.00
/
Size

Order now, ships by:

Product Description

Recombinant Human GITR/TNFRSF18 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Glu161.

Product Background

GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.

Product Category

Recombinant Protein / Antibody discovery / Immune checkpoint proteins

Protein

GITR/TNFRSF18

Synonyms

CD357; GITR; GITR-D; TNFRSF18; AITR

Accession

Species

Human

Biotinylated

no

Amino Acid Range

Gln26-Glu161

Molecular Weight

The protein has a predicted MW of 41.3 kDa. Due to glycosylation, the protein migrates to 45-55 kDa based on Bis-Tris PAGE result.

Activity

Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Expression System

HEK293

Purity

> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Endotoxin

Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
-20 to -80°C for 12 months as supplied from date of receipt.;-80°C for 3 months after reconstitution.;Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA. Immobilized Human GITR Ligand Trimer, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human GITR, hFc Tag with the EC50 of 50.8ng/ml determined by ELISA.
Human GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human GITR on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human GITR is greater than 95% as determined by SEC-HPLC. The purity of Human GITR is greater than 95% as determined by SEC-HPLC.

Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

Recently viewed