Product Description |
Recombinant Human gp130/CD130/IL-6 R beta-Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Glu23-Glu619. |
Product Background |
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic factor, and cardiotrophin-1. These cytokines exhibit pleiotropic biological activities in, for instance, immune, hematopoietic, and neural systems, and function in a redundant manner owing to the shared usage of gp130. |
Product Category |
Recombinant Protein |
Target |
gp130/CD130/IL-6 R beta |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu23-Glu619 |
Molecular Weight |
The protein has a predicted MW of 68.94 kDa. Due to glycosylation, the protein migrates to 80-110 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human gp130 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human gp130 is greater than 95% as determined by SEC-HPLC. |
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