Human GPR75 VLP (GPR-HM00V)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA.
Amino Acid Range: Met1-Val540

Catalog #GPR-HM00V

Price

$1,235.00

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Human GPR75 VLP (GPR-HM00V) Summary

Product Description	Recombinant Human GPR75 VLP is expressed from HEK293.It contains Met1-Val540 (It may have cross reaction with anti-His antibody).
Product Background	G protein-coupled receptor 75 (GPR75), a novel member of the rhodopsin-like G protein-coupled receptor (GPCR) family, has been identified across various tissues and organs, where it contributes to biological regulation and disease progression. GPR75 might interact with the C-C motif chemokine ligand 5 (CCL5, also known as RANTES), influencing nervous system functions. GPR75 may also bind to 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite of cytochrome P450 (CYP450) enzymes , highlighting its roles in the nervous, cardiovascular, and endocrine systems and its potential involvement in neurodegenerative diseases, hypertension, and metabolic syndrome.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / VLP

Protein	GPR75
Synonyms	WI-31133; GPRchr2; WI31133
Accession	O95800
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Val540
Molecular Weight	The target protein has a predicted MW of 89.57 kDa.
Activity	Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA.
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA.
	The purity of Human GPR75 VLP is greater than 95% as determined by SEC-HPLC.

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