• Express System: HEK293
  • Purity: > 95% as determined by HPLC
  • Activity: Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA.
  • Amino Acid Range: Met1-Val540
Catalog #GPR-HM00V
Price
Regular price $1,23500
Regular price Sale price $1,23500
/
Size
Avantor VWR Fisher Scientific

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Human GPR75 VLP (GPR-HM00V) Summary

Product Description

 Recombinant Human GPR75 VLP is expressed from HEK293.It contains Met1-Val540 (It may have cross reaction with anti-His antibody).

Product Background

 G protein-coupled receptor 75 (GPR75), a novel member of the rhodopsin-like G protein-coupled receptor (GPCR) family, has been identified across various tissues and organs, where it contributes to biological regulation and disease progression. GPR75 might interact with the C-C motif chemokine ligand 5 (CCL5, also known as RANTES), influencing nervous system functions. GPR75 may also bind to 20-hydroxyeicosatetraenoic acid (20-HETE), a metabolite of cytochrome P450 (CYP450) enzymes , highlighting its roles in the nervous, cardiovascular, and endocrine systems and its potential involvement in neurodegenerative diseases, hypertension, and metabolic syndrome.

Human GPR75 VLP (GPR-HM00V) Specifications/Details

Protein
 GPR75
Synonyms
 WI-31133; GPRchr2; WI31133
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Met1-Val540
Molecular Weight
 The target protein has a predicted MW of 89.57 kDa.
Activity
 Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA.
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS, 300mM L-arginine (pH 7.4). Notice: If you need it for immunization, water-soluble adjuvant is recommended.
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA. Immobilized Human GPR75 VLP at 5ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPR75 Antibody, hFc Tag with the EC50 of 54.2ng/ml determined by ELISA.
The purity of Human GPR75 VLP is greater than 95% as determined by SEC-HPLC. The purity of Human GPR75 VLP is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...