- Express System: HEK293
- Product Tag: C-His
- Activity: Immobilized Human GPRC5D Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. The affinity constant of 1.47 nM as determined in SPR assay (Biacore T200).
- Amino Acid Range: Met1-Val345
Human GPRC5D Nanodisc (GPR-HM15P) Summary
Product Description |
Recombinant Human GPRC5D Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val345. |
Product Background |
G protein–coupled receptor, family C, group 5, member D (GPRC5D) is an orphan receptor that is primarily expressed in plasma cells and hard keratinized tissues, with low expression in normal human tissues. GPRC5D expression is enriched in malignant plasma cells and is associated with markers of high-risk myeloma. |
Product Category |
Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc |
Human GPRC5D Nanodisc (GPR-HM15P) Specifications/Details
Protein |
GPRC5D |
Synonyms |
GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Met1-Val345 |
Molecular Weight |
The protein has a predicted MW of 39.6 kDa. |
Activity |
Immobilized Human GPRC5D Nanodisc, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 5.8ng/ml determined by ELISA. The affinity constant of 1.47 nM as determined in SPR assay (Biacore T200). |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS, 200mM L-arginine (pH 7.4). |
Stability And Storage |
Valid for 6 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
Other Available Proteins:
Finding available proteins...
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