Name: Human GPRC5D Protein-Nanodisc (GPR-HM15P)
Brand: KactusBio
SKU: GPR-HM15P-100UG
Price: 1100.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Activity: Immobilized Human GPRC5D Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test). The affinity constant of 1.47 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Met1-Val345

Catalog #GPR-HM15P

Size

100UG

Order now, ships by:

Product Description	Recombinant Human GPRC5D Protein-Nanodisc is expressed from HEK293 with His tag at the C-terminus.It contains Met1-Val345.
Product Background	Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Product Category	Recombinant Protein / Antibody discovery / Multiple transmembrane proteins / Nanodisc

Protein	GPRC5D
Synonyms	GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Accession	Q9NZD1-1
Species	Human
Biotinylated	no
Amino Acid Range	Met1-Val345
Molecular Weight	The protein has a predicted MW of 42.10 kDa.
Activity	Immobilized Human GPRC5D Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test). The affinity constant of 1.47 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4). Notice: Not recommended for immunization and flow cytometry in mammalian cells.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human GPRC5D Nanodisc, His Tag captured on CM5 Chip via anti-his antibody can bind Anti-GPRC5D Antibody with an affinity constant of 1.47 nM as determined in SPR assay (Biacore T200).
	Immobilized Human GPRC5D Nanodisc, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 4.9ng/ml determined by ELISA (QC Test).