Human GPRC5D Protein-VLP (GPR-HM05P)

Express System: HEK293
Purity: > 95% as determined by HPLC
Activity: Immobilized Human GPRC5D VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA. See testing image for detail.
Exact Sequence: Met1-Val345

Catalog: GPR-HM05P

Order now get it on

Bulk Quote | Test Sample

Product Description	Recombinant Human GPRC5D Protein-VLP is expressed from HEK293.It contains Met1-Val345.
Product Background	Chimeric antigen receptor (CAR) T cells, a type of cell-based immunotherapy, have shown some promising results in multiple myeloma, a bone marrow cancer.The orphan G protein–coupled receptor, class C group 5 member D (GPRC5D), normally expressed only in the hair follicle, Using quantitative immunofluorescence, we determined that GPRC5D protein is expressed on CD138 MM cells from primary marrow samples with a distribution that was similar to, but independent of, BCMA.
Product Category	Recombinant Protein

Target	GPRC5D
Synonyms	GPRC5D; MGC129713; MGC129714; orphan G-protein coupled receptor
Gene/Protein ID	Q9NZD1-1
Species	Human
Exact Sequence	Met1-Val345
Molecular Weight	The target protein has a predicted MW of 39.6 kDa.
Activity	Immobilized Human GPRC5D VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA. See testing image for detail.
Express System	HEK293
Purity	> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in PBS (pH 7.4). Notice: If you need it for immunization, Do Not use any adjuvant.
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human GPRC5D VLP at 5ug/ml (100ul/Well) on the plate. Dose response curve for Anti-GPRC5D Antibody, hFc Tag with the EC50 of 6.9ng/ml determined by ELISA.
	The purity of Human GPRC5D VLP is greater than 95% as determined by SEC-HPLC.