Name: Human/Cynomolgus Her4/ErbB4 Protein (HER-HM204)
Brand: KactusBio
SKU: HER-HM204-100UG
Price: 237.6 USD
Availability: InStock

Human/Cynomolgus Her4/ErbB4 Protein (HER-HM204)

Immobilized Human/Cynomolgus Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA.

Human/Cynomolgus Her4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human/Cynomolgus Her4 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human/Cynomolgus Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA. See testing image for detail.
Amino Acid Range: Gln26-Pro651

Catalog #HER-HM204

Size

100UG

500UG

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Product Description	Recombinant Human/Cynomolgus Her4/ErbB4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Pro651.
Product Background	ErbB4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between ErbB4 and type 2 diabetes and obesity. ErbB4 may play an important role in glucose homeostasis and lipogenesis. ErbB4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS.
Product Category	Recombinant Protein / Antibody discovery / CAR-T targets

Protein	Her4/ErbB4
Synonyms	p180erbB4; 4ICD; E4ICD; HER4; ErbB4; MGC138404; ALS19
Accession	Q15303-1(Human) / A0A2K5W0D7(Cynomolgus)
Species	Human/Cynomolgus
Biotinylated	no
Amino Acid Range	Gln26-Pro651
Molecular Weight	The protein has a predicted MW of 96.6 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human/Cynomolgus Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA. See testing image for detail.
Product Tag	C-hFc
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 24 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human/Cynomolgus Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA.
	Human/Cynomolgus Her4 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human/Cynomolgus Her4 is greater than 95% as determined by SEC-HPLC.