Human Her4/ErbB4 Protein (HER-HM204)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA. See testing image for detail.
  • Amino Acid Range: Gln26-Pro651

Catalog: HER-HM204

$216.00
Size:

Order now get it on

Product Description Recombinant Human Her4/ErbB4 Protein is expressed from HEK293 with hFc tag at the C-Terminus.It contains Gln26-Pro651.

Product Background

ErbB4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between ErbB4 and type 2 diabetes and obesity. ErbB4 may play an important role in glucose homeostasis and lipogenesis. ErbB4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS.

Product Category

Recombinant Protein

Target

Her4/ErbB4
Synonyms p180erbB4; 4ICD; E4ICD; HER4; ErbB4; MGC138404; ALS19
Accession

Species

Human

Amino Acid Range

Gln26-Pro651
Molecular Weight The protein has a predicted MW of 96.6 kDa. Due to glycosylation, the protein migrates to 100-120 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Lyophilized
Shipping Shipped at ambient temperature.
Formulation Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Immobilized Human Her4, hFc Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human NRG1 Beta 1, hFc Tag with the EC50 of 94.6ng/ml determined by ELISA.
The purity of Human Her4 is greater than 95% as determined by SEC-HPLC.
Human Her4 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

You may also be interested in