Regular price
$825.00
Order by 4pm ET for delivery on:
Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein (MHC-HM493T) Summary
Product Description |
Recombinant Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide. |
Product Background |
Kita-Kyushu lung cancer antigen-1 (KK-LC-1), encoded by CT83, includes epitope peptides recognized by cytotoxic T lymphocytes (CTLs). CTLs against KK-LC-1 predominantly accumulate among tumor-infiltrating lymphocytes, which leads to a good response to adaptive immunotherapy. Except for the testis, KK-LC-1 is not expressed in normal tissues. It is expressed in 33%, 82%, and 75% of non-small cell lung cancers, GC, and triple-negative breast cancers, respectively. |
Product Category |
Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs |
HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Specifications
Protein |
HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) |
Synonyms |
KK-LC-1; CT83; CXorf61; KKLC1; |
MHC Form |
Tetramer |
Allele |
HLA-A*02:01 |
Accession |
A0A140T913(HLA-A*02:01)&P61769(B2M)&ILNNFPHSI |
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and ILNNFPHSI peptide |
Molecular Weight |
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reduced (N) condition based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
|
|
Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer on Bis-Tris PAGE under Non reduced (N) condition. The purity is greater than 95%. |
|
|
The purity of Human HLA-A*02:01&B2M&KKLC1 (ILNNFPHSI) Tetramer is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
Related Products
Have more questions?
Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.
Contact Us
Recommended Products
Loading...
Recently viewed
