Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein (MHC-HM459)
Catalog: MHC-HM459
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Product Description | Recombinant Human HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide. |
Product Background |
MAGE-A10 is a subtype of the Melanoma-associated antigen A (MAGE-A), a class of tumor antigens that are extensively expressed in various histological types of tumors and represents an attractive target for tumor immunotherapy. High-level expression of MAGE-A10 improved the anti-tumor immune cytotoxicity of MAGE-A10-specific CTLs in lung cancer cell lines and primary lung cancer cells. |
Product Category |
Recombinant Protein |
Target |
HLA-A*02:01&B2M&MAGE-A10 (GLYDGMEHL) Monomer |
MHC Form | Monomer |
Allele | HLA-A*02:01 |
Gene/Protein ID |
A0A140T913(HLA-A*02:01)&P61769(B2M)&GLYDGMEHL |
Species |
Human |
Exact Sequence |
Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and GLYDGMEHL peptide |
Molecular Weight | The protein has a predicted MW of 50.44 kDa. Due to glycosylation, the protein migrates to 53-63 kDa based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
Endotoxin | Less than 1EU per ug by the LAL method. |
Form | Liquid |
Shipping | Shipped with dry ice. |
Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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