Name: Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer Protein (MHC-HM4A1T)
Brand: KactusBio
SKU: MHC-HM4A1T-100UG
Price: 825.0 USD
Availability: InStock

Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer Protein (MHC-HM4A1T)

Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer on Bis-Tris PAGE under Non reduced (N) condition. The purity is greater than 95%.

The purity of Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and LTLGEFLKL peptide

Catalog #MHC-HM4A1T

Size

100UG

500UG

Order by 4pm ET for delivery on:

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Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer Protein (MHC-HM4A1T) Summary

Product Description	Recombinant Human HLA-A02:01&B2M&Survivin (LTLGEFLKL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A02:01), Ile21-Met119(B2M) and LTLGEFLKL peptide.
Product Background	Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upregulated in most, if not all cancers; consequently, it has received significant attention as a potential oncotherapeutic target.
Product Category	Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Specifications

Protein	HLA-A*02:01&B2M&Survivin (LTLGEFLKL)
Synonyms	Survivin; MHC; MHC I; BIRC5; API4; EPR-1; IAP4; survivin variant 3 alpha
MHC Form	Tetramer
Allele	HLA-A*02:01
Accession	A0A140T913(HLA-A*02:01)&P61769(B2M)<LGEFLKL
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and LTLGEFLKL peptide
Molecular Weight	The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reduced (N) condition based on Bis-Tris PAGE result.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer on Bis-Tris PAGE under Non reduced (N) condition. The purity is greater than 95%.
	The purity of Human HLA-A*02:01&B2M&Survivin (LTLGEFLKL) Tetramer is greater than 95% as determined by SEC-HPLC.