• Express System: E.coli
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ILRGSVAHK peptide
Catalog #MHC-HE470
Price
Regular price $34100
Regular price Sale price $34100
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Size
Avantor VWR Fisher Scientific

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Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer Protein (MHC-HE470) Summary

Product Description

Recombinant Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ILRGSVAHK peptide.

Product Background

Influenza A virus (IAV) is a respiratory pathogen that causes seasonal epidemics with significant mortality. Influenza virus genome encapsidation is essential for the formation of a helical viral ribonucleoprotein (vRNP) complex composed of nucleoproteins (NP), the trimeric polymerase, and the viral genome. The RNA, located at the interface of neighboring NP protomers, interacts with conserved residues previously described as essential for the NP-RNA interaction. The NP undergoes conformational changes to enable RNA binding and helix formation.

HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Specifications

Protein
HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK)
Synonyms
Influenza NP; ILRGSVAHK
MHC Form
Monomer
Allele
HLA-A*03:01
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ILRGSVAHK peptide
Molecular Weight
The protein has a predicted MW of 35.39 kDa (HLA-A*03:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Product Tag
C-His-Avi
Fluorophore
Unconjugated
Expression System
E.coli
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC

Shipping, Reconstitution, & Storage

Form
Liquid
Shipping
Shipped with dry ice.
Formulation
Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Stability And Storage
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer is greater than 95% as determined by SEC-HPLC. The purity of Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...