- Express System: E.coli
- Product Tag: C-His-Avi
- Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
- Amino Acid Range: Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ILRGSVAHK peptide
Product Description |
Recombinant Human HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ILRGSVAHK peptide. |
Product Background |
Influenza A virus (IAV) is a respiratory pathogen that causes seasonal epidemics with significant mortality. Influenza virus genome encapsidation is essential for the formation of a helical viral ribonucleoprotein (vRNP) complex composed of nucleoproteins (NP), the trimeric polymerase, and the viral genome. The RNA, located at the interface of neighboring NP protomers, interacts with conserved residues previously described as essential for the NP-RNA interaction. The NP undergoes conformational changes to enable RNA binding and helix formation. |
Product Category |
Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs |
Protein |
HLA-A*03:01&B2M&Influenza NP (ILRGSVAHK) |
Synonyms |
Influenza NP; ILRGSVAHK |
MHC Form |
Monomer |
Allele |
HLA-A*03:01 |
Accession |
NP_002107.3(HLA-A*03:01)&P61769(B2M)&ILRGSVAHK |
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and ILRGSVAHK peptide |
Molecular Weight |
The protein has a predicted MW of 35.39 kDa (HLA-A*03:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Fluorophore |
Unconjugated |
Expression System |
E.coli |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl (pH 8.0). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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