Name: Human HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein (MHC-HE014)
Brand: KactusBio
SKU: MHC-HE014-100UG
Price: 310.0 USD
Availability: InStock

Human HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein (MHC-HE014)

Express System: E.coli
Product Tag: C-His-Avi
Purity: >95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Amino Acid Range: Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and VVVGADGVGK peptide

Catalog #MHC-HE014

Size

100UG

500UG

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Product Description	Recombinant Human HLA-A03:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein is expressed from E.coli with His tag and Avi tag at the C-terminus.It contains Gly25-Thr305(HLA-A03:01), Ile21-Met119(B2M) and VVVGADGVGK peptide.
Product Background	Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-priority therapeutic target. The virtual screening approach to discover novel KRAS inhibitors and synthetic lethality interactors of KRAS are discussed in detail.
Product Category	Recombinant Protein

Target	HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Monomer
MHC Form	Monomer
Allele	HLA-A*03:01
Accession	NP_002107.3(HLA-A*03:01)&P61769(B2M)&VVVGADGVGK
Species	Human
Biotinylated	no
Amino Acid Range	Gly25-Thr305(HLA-A*03:01), Ile21-Met119(B2M) and VVVGADGVGK peptide
Molecular Weight	The protein has a predicted MW of 35.26 kDa (HLA-A*03:01) and 11.9 kDa (B2M) same as Bis-Tris PAGE result.
Product Tag	C-His-Avi
Express System	E.coli
Purity	>95% as determined by Bis-Tris PAGE;>95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in 20mM Tris, 200mM NaCl (pH 8.0).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Monomer on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human HLA-A*03:01&B2M&KRAS G12D (VVVGADGVGK) Monomer is greater than 95% as determined by SEC-HPLC.