Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein (MHC-HM464T)

  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVCPICSQK peptide

Catalog: MHC-HM464T

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Product Description Recombinant Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and IVCPICSQK peptide.

Product Background

HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.

Product Category

Recombinant Protein

Target

HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer
Accession
MHC Form Tetramer
Allele HLA-A*11:01

Species

Human

Amino Acid Range

Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVCPICSQK peptide
Molecular Weight The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result.

Product Tag

C-His-Avi

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
The purity of Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein is greater than 95% as determined by SEC-HPLC.
Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein on Tris-Bis PAGE under Non reducing (N) condition. The purity is greater than 95%.

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