Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein (MHC-HM464T)
Catalog: MHC-HM464T
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| Product Description | Recombinant Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and IVCPICSQK peptide. |
Product Background |
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody. |
Product Category |
Recombinant Protein |
Target |
HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer |
| Accession | |
| MHC Form | Tetramer |
| Allele | HLA-A*11:01 |
Species |
Human |
Amino Acid Range |
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVCPICSQK peptide |
| Molecular Weight | The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Tris-Bis PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
| Purity | > 95% as determined by Tris-Bis PAGE;> 95% as determined by HPLC |
| Endotoxin | Less than 1EU per ug by the LAL method. |
| Form | Liquid |
| Shipping | Shipped with dry ice. |
| Formulation | Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
| Stability And Storage | Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
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The purity of Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein is greater than 95% as determined by SEC-HPLC. |
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Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein on Tris-Bis PAGE under Non reducing (N) condition. The purity is greater than 95%. |
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