Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein (MHC-HM464T)
Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein (MHC-HM464T)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVCPICSQK peptide
Catalog #MHC-HM464T
Regular price $750.00
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Product Description
Recombinant Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305 (HLA-A*11:01), Ile21-Met119 (B2M) and IVCPICSQK peptide.
Product Background
HPV16 E7 protein, one of the primary target proteins in molecular targeted therapy for HPV-induced cervical cancer. The affitoxin, ZHPV16E7 affitoxin384 was generated by fusing the modified Pseudomonas Exotoxin A (PE38KDEL) to the HPV16 E7-specific affibody.
Product Category
Recombinant Protein
Target
HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer
MHC Form
Tetramer
Allele
HLA-A*11:01
Accession
Species
Human
Biotinylated
no
Amino Acid Range
Gly25-Thr305(HLA-A*11:01), Ile21-Met119(B2M) and IVCPICSQK peptide
Molecular Weight
The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reducing (N) condition based on Bis-Tris PAGE result.
Product Tag
C-His-Avi
Express System
HEK293
Purity
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
Less than 1EU per ug by the LAL method.
Form
Lyophilized
Shipping
Shipped at ambient temperature.
Formulation
Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein on Bis-Tris PAGE under Non reducing (N) condition. The purity is greater than 95%.
The purity of Human HLA-A*11:01&B2M&HPV16 E7 (IVCPICSQK) Tetramer Protein is greater than 95% as determined by SEC-HPLC.

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