Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein (MHC-HM436T)
  • Express System: HEK293
  • Product Tag: C-His-Avi
  • Purity: > 95% as determined by Bis-Tris PAGE
  • Amino Acid Range: Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLPQLCTEL peptide
  • Other Available Proteins:
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Catalog #MHC-HM436T
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Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein (MHC-HM436T) Summary

Product Description

 Recombinant Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus, tetramer is assembled by biotinylated monomer and streptavidin.It contains Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLPQLCTEL peptide.

Product Background

 Human papillomavirus (HPV) 16 infection is a necessary condition for the pathogenesis and development of cervical cancer. The E6 protein is expressed by the HPV16 E6 gene and promotes malignant phenotype transformation, which is an important mechanism for the occurrence and development of cervical cancer.

Product Category

 Recombinant Protein / Antibody discovery / MHC / Peptide-MHCs

HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Specifications

Protein
 HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL)
Synonyms
 Human papillomavirus type 16; HPV16; E6;

MHC Form

 Tetramer

Allele

 HLA-A*02:01
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Gly25-Thr305(HLA-A*02:01), Ile21-Met119(B2M) and KLPQLCTEL peptide
Molecular Weight
 The protein has a predicted MW of 258 kDa. Due to glycosylation, the protein migrates to 260-265 kDa under Non reduced (N) condition based on Bis-Tris PAGE result.
Product Tag
 C-His-Avi

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer on Bis-Tris PAGE under Non reduced (N) condition. The purity is greater than 95%. Human HLA-A*02:01&B2M&HPV 16 E6 (KLPQLCTEL) Tetramer on Bis-Tris PAGE under Non reduced (N) condition. The purity is greater than 95%.
Have more questions?

Check out our Frequently Asked Questions page for more details about product specifications, ordering, and shipments.

Contact Us

support@kactusbio.us

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