Name: Human IDH1 Protein (IDH-HE101)
Brand: KactusBio
SKU: IDH-HE101-100UG
Price: 270.0 USD
Availability: InStock

Catalog #IDH-HE101

Size

100UG

500UG

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Product Description	Recombinant Human IDH1 Protein is expressed from E.coli with His tag at the C-Terminus.It contains Ser2-Leu414.
Product Background	Isocitrate dehydrogenase (IDH) is a metabolic enzyme that converts isocitrate to α-ketoglutarate (α-KG). Genetic gain-of-function mutations in IDH1 and IDH2 confer a neomorphic activity that allow reduction of α -KG to (R)-2- hydroxyglutarate, the accumulation of which results in the development of cancers like low grade gliomas and leukemia.Isocitrate dehydrogenase 1 (IDH1) is the most frequently mutated metabolic gene in cancer.
Product Category	Recombinant Protein / Antibody discovery

Protein	IDH1
Synonyms	IDH; IDH1; IDPc; PICD; IDP; DCD; IDH; Isocitrate dehydrogenase; IDCD;
Accession	O75874
Species	Human
Biotinylated	no
Amino Acid Range	Ser2-Leu414
Molecular Weight	The protein has a predicted MW of 47.35 kDa same as Bis-Tris PAGE result.
Product Tag	C-His
Expression System	E.coli
Purity	> 95% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22um filtered solution in 50mM Tris, 200mM NaCl, 1mM DTT, 10% Glycerol (pH 7.5).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IDH1 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IDH1 is greater than 95% as determined by SEC-HPLC.