Name: Human IFN alpha/beta R1 Protein (IFN-HM4R1)
Brand: KactusBio
SKU: IFN-HM4R1-100UG
Price: 330.0 USD
Availability: InStock

Human IFN alpha/beta R1 Protein (IFN-HM4R1)

Human IFN alpha/beta R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 0.12 uM as determined in SPR assay (Biacore T200).

Immobilized Human IFN alpha/beta R1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IFN alpha/beta R1 Antibody, hFc Tag with the EC50 of 16.0ng/ml determined by ELISA (QC Test).

Human IFN alpha/beta R1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.

The purity of-Human IFN alpha/beta R1 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His-Avi
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IFN alpha/beta R1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IFN alpha/beta R1 Antibody, hFc Tag with the EC50 of 16.0ng/ml determined by ELISA (QC Test). The affinity constant of 0.12 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Lys28-Lys436

Catalog #IFN-HM4R1

Size

100UG

500UG

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Product Description	Recombinant Human IFN alpha/beta R1 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Lys28-Lys436.
Product Background	IFN-alpha / beta R1, also known as IFNAR1, belongs to the class II cytokine receptor family of proteins. Class II cytokine receptors form heterodimeric receptor complexes that mediate class II cytokine signals. Subunits of the different receptor complexes are shared and serve multiple functions.Functions in general as heterodimer with IFNAR2. Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves.
Product Category	Recombinant Protein / Antibody discovery

Protein	IFN alpha/beta R1
Synonyms	AVP; IFN-alpha/beta R1; IFN-alpha-REC; IFNAR; IFNAR1; IFN-aR1; IFNBR; IFNbR1; IFN-R-1; CRF2-1; IFRC ; IFN-alpha/β R1
Accession	P17181-1
Species	Human
Biotinylated	no
Amino Acid Range	Lys28-Lys436
Molecular Weight	The protein has a predicted MW of 50.2 kDa. Due to glycosylation, the protein migrates to 74-95 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IFN alpha/beta R1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IFN alpha/beta R1 Antibody, hFc Tag with the EC50 of 16.0ng/ml determined by ELISA (QC Test). The affinity constant of 0.12 uM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His-Avi
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IFN alpha/beta R1, His Tag captured on CM5 Chip via anti-his antibody can bind Human IFN alpha 1, hFc Tag with an affinity constant of 0.12 uM as determined in SPR assay (Biacore T200).
	Immobilized Human IFN alpha/beta R1, His Tag at 2ug/ml (100ul/well) on the plate. Dose response curve for Anti-IFN alpha/beta R1 Antibody, hFc Tag with the EC50 of 16.0ng/ml determined by ELISA (QC Test).
	Human IFN alpha/beta R1 on Bis-Tris PAGE under reduced conditions. The purity is greater than 95%.
	The purity of-Human IFN alpha/beta R1 is greater than 95% as determined by SEC-HPLC.