Name: Human IgE Protein (IGE-HM101)
Brand: KactusBio
SKU: IGE-HM101-100UG
Price: 375.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Activity: Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 1.5ng/ml determined by ELISA.
Amino Acid Range: Cys209-Lys428

Catalog #IGE-HM101

Size

100UG

500UG

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Human IgE Protein (IGE-HM101) Summary

Product Description	Recombinant Human IgE Protein is expressed from HEK293 with His tag at the C-terminus.It contains Cys209-Lys428.
Product Background	Immunoglobulin E (IgE) is well known for its role in allergic disease, the manifestations of which are mediated through its two Fc receptors, FcεRI and CD23 (FcεRII). IgE and its interactions with these receptors are therefore potential targets for therapeutic intervention, and exciting progress has been made in this direction. Furthermore, recent structural studies of IgE-Fc, the two receptors, and of their complexes, have revealed a remarkable degree of plasticity at the IgE-CD23 interface and an even more remarkable degree of dynamic flexibility within the IgE molecule.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery \| Others

Human IgE Protein (IGE-HM101) Specifications/Details

Protein	IgE
Synonyms	Ig epsilon chain C region;IgE
Accession	P01854-1
Species	Human
Biotinylated	no
Amino Acid Range	Cys209-Lys428
Molecular Weight	The protein has a predicted MW of 26.18 kDa. Due to glycosylation, the protein migrates to 35-40 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 1.5ng/ml determined by ELISA.
Product Tag	C-His
Expression System	HEK293
Purity	> 90% as determined by Bis-Tris PAGE;> 90% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human Fc epsilon RI alpha, hFc Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Human IgE, His Tag with the EC50 of 1.5ng/ml determined by ELISA.
	Immobilized Human IgE, His Tag at 0.5ug/ml (100ul/well) on the plate. Dose response curve for Omalizumab, hFc Tag with the EC50 of 5.1ng/ml determined by ELISA.
	Human IgE on Bis-Tris PAGE under reduced condition. The purity is greater than 90%.
	The purity of Human IgE is greater than 90% as determined by SEC-HPLC.