Product Description |
Recombinant Human IGF2R Domain 1-3 Protein is expressed from HEK293 with His tag and Avi tag at the C-Terminus.It contains Glu47-Lys468. |
Product Background |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. |
Product Category |
Recombinant Protein |
Target |
IGF2R Domain 1-3 |
Synonyms |
CI-MPR; M6PR; MPR 300; IGF-II receptor; M6P/IGF2R; CD222; MPRI |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Glu47-Lys468 |
Molecular Weight |
The protein has a predicted MW of 50.50 kDa. Due to glycosylation, the protein migrates to 55-65 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His-Avi |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human IGF2R Domain 1-3 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human IGF2R Domain 1-3 is greater than 95% as determined by SEC-HPLC. |
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