Human IGFBP-7 Protein (IGF-HM207)

Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.40ug/ml determined by ELISA (QC Test).

Human IGFBP-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IGFBP-7 is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.40ug/ml determined by ELISA (QC Test).
Amino Acid Range: Ser27-Leu282

Catalog #IGF-HM207

Price

$346⁵⁰

Size

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Human IGFBP-7 Protein (IGF-HM207) Summary

Product Description

Recombinant Human IGFBP-7 Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Ser27-Leu282.

Product Background

IGFBP-7, also known as Mac25/Angiomodulin (AGM), GFBP-rp1, tumor-derived adhesion factor (TAF) and prostacyclin-stimulating factor (PSF), is a secreted protein that contains three protein domain modules. Human IGFBP-rp1 cDNA encodes 282 amino acid (aa) residue precursor protein with a putative 26 aa signal peptide. IGFBP-7 binds IGF-I and IGF-II with a relatively low affinity. Stimulates prostacyclin (PGI2) production. Stimulates cell adhesion.

Human IGFBP-7 Protein (IGF-HM207) Specifications/Details

Protein	IGFBP-7
Synonyms	IGFBP-7; IBP7; AGM; FSTL2; IGFBP-7v; IGFBPRP1; MAC25; PSF; RAMSVPS; TAF;IGFBP7; IGFBP7v
Accession	Q16270
Species	Human
Biotinylated	no
Amino Acid Range	Ser27-Leu282
Molecular Weight	The protein has a predicted MW of 53.20 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.40ug/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human CD93, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Human IGFBP-7, hFc Tag with the EC50 of 0.40ug/ml determined by ELISA (QC Test).
	Human IGFBP-7 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IGFBP-7 is greater than 95% as determined by SEC-HPLC.