Product Description |
Recombinant Human IGFBP2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala36-Gln325. |
Product Background |
Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly decreases after birth. Aberrant expression of IGFBP2 in cancer acts as a hub of an oncogenic network, integrating multiple cancer signaling pathways and serving as a potential therapeutic target for cancer treatment. |
Product Category |
Recombinant Protein |
Target |
IGFBP2 |
Synonyms |
IBP-2; IGFBP-2; BP2; AI255832; mIGFBP-2; IGFBP2; IGF-BP53 |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Ala36-Gln325 |
Molecular Weight |
The protein has a predicted MW of 32.5 kDa. Due to glycosylation, the protein migrates to 33-40 kDa based on Bis-Tris PAGE result. |
Product Tag |
C-His |
Express System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1EU per ug by the LAL method. |
Form |
Lyophilized |
Shipping |
Shipped at ambient temperature. |
Formulation |
Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization. |
Reconstitution |
Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water. |
Stability And Storage |
Reconstituted protein stable at -80°C for 12 months, 4°C for 1 week. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. |
|
|
Human IGFBP2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
|
|
The purity of Human IGFBP2 is greater than 95% as determined by SEC-HPLC. |
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