• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Amino Acid Range: Ala36-Gln325
Catalog #IGF-HM102
Price
Regular price $29700
Regular price Sale price $29700
/
Size
Avantor VWR Fisher Scientific

Order by 4pm ET for delivery on:

Human IGFBP-2 Protein (IGF-HM102) Summary

Product Description

 Recombinant Human IGFBP-2 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Ala36-Gln325.

Product Background

 Insulin-like growth factor (IGF) binding protein 2 (IGFBP2) was discovered and identified as an IGF system regulator, controlling the distribution, function, and activity of IGFs in the pericellular space. IGFBP2 is a developmentally regulated gene that is highly expressed in embryonic and fetal tissues and markedly decreases after birth. Aberrant expression of IGFBP2 in cancer acts as a hub of an oncogenic network, integrating multiple cancer signaling pathways and serving as a potential therapeutic target for cancer treatment.

Human IGFBP-2 Protein (IGF-HM102) Specifications/Details

Protein
 IGFBP-2
Synonyms
 IBP-2; IGFBP-2; BP2; AI255832; mIGFBP-2; IGFBP2; IGF-BP53;IBP2
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Ala36-Gln325
Molecular Weight
 The protein has a predicted MW of 32.5 kDa. Due to glycosylation, the protein migrates to 33-40 kDa based on Bis-Tris PAGE result.
Product Tag
 C-His
Fluorophore
 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Lyophilized
Shipping
 Shipped at ambient temperature.
Formulation
 Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution
 Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage
 -20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Human IGFBP-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IGFBP-2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IGFBP-2 is greater than 95% as determined by SEC-HPLC. The purity of Human IGFBP-2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...