• Express System: HEK293
  • Product Tag: C-His
  • Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
  • Activity: Immobilized Human IL-1 Rrp2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA.
  • Amino Acid Range: Asp20-Arg335
Catalog #IL1-HM1L3
Price
Regular price $270.00
Regular price Sale price $270.00
/
Size
Avantor VWR Fisher Scientific

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Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM1L3) Summary

Product Description

 Recombinant Human IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asp20-Arg335.

Product Background

 The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways.

Product Category

 Recombinant Protein / Antibody discovery / Antibody discovery | Others

Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM1L3) Specifications/Details

Protein
 IL-1 Rrp2/IL-1 R6
Synonyms
 IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R
Accession
Species
 Human
Biotinylated
 no
Amino Acid Range
 Asp20-Arg335
Molecular Weight
 The protein has a predicted MW of 37.55 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result.
Activity
 Immobilized Human IL-1 Rrp2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA.
Product Tag
 C-His

Fluorophore

 Unconjugated
Expression System
 HEK293
Purity
 > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin
 Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form
 Liquid
Shipping
 Shipped with dry ice.
Formulation
 Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage
 Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

Immobilized Human IL-1 Rrp2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA. Immobilized Human IL-1 Rrp2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA.
Human IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. Human IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
The purity of Human IL-1 Rrp2 is greater than 95% as determined by SEC-HPLC. The purity of Human IL-1 Rrp2 is greater than 95% as determined by SEC-HPLC.
Other Available Proteins:
Finding available proteins...
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