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Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM1L3) Summary
Product Description |
Recombinant Human IL-1 Rrp2/IL-1 R6 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Asp20-Arg335. |
Product Background |
The Interleukin 1 receptor family (IL-1 R) comprises at least eleven members including IL-1 RI (IL-1 R1), IL-1 RII (IL-1 R2), IL-1 RAcP (IL‑1 R3), ST2 (T1/IL-1 R4), IL-18 Ra (IL-1 Rrp/IL-1 R5), IL-1 Rrp2 (IL-1 RL2/IL-1 R6), IL-18 Rb (AcPL/IL-1 R7), IL-1RAPL‑1 (TIGIRR‑2/IL‑1 R8), and TIGIRR-1 (IL-1 R9). IL1RL2 is a receptor for interleukin-36 (IL36A, IL36B and IL36G). After binding to interleukin-36 associates with the coreceptor IL1RAP to form the interleukin-36 receptor complex which mediates interleukin-36-dependent activation of NF-kappa-B, MAPK and other pathways. |
Product Category |
Recombinant Protein / Antibody discovery / Antibody discovery | Others |
Human IL-1 Rrp2/IL-1 R6 Protein (IL1-HM1L3) Specifications/Details
Protein |
IL-1 Rrp2/IL-1 R6 |
Synonyms |
IL-1 R6; IL-1 Rrp2; IL1RL2; IL1Rrp2; IL1RRP2; IL-36R |
Accession |
|
Species |
Human |
Biotinylated |
no |
Amino Acid Range |
Asp20-Arg335 |
Molecular Weight |
The protein has a predicted MW of 37.55 kDa. Due to glycosylation, the protein migrates to 55-70 kDa based on Bis-Tris PAGE result. |
Activity |
Immobilized Human IL-1 Rrp2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA. |
Product Tag |
C-His |
Fluorophore |
Unconjugated |
Expression System |
HEK293 |
Purity |
> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC |
Endotoxin |
Less than 1 EU per ug by the LAL method. |
Shipping, Reconstitution, & Storage
Form |
Liquid |
Shipping |
Shipped with dry ice. |
Formulation |
Supplied as 0.22 um filtered solution in PBS (pH 7.4). |
Stability And Storage |
Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles. |
Validation Images
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Immobilized Human IL-1 Rrp2, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Anti-IL-1 Rrp2 Antibody, hFc Tag with the EC50 of 7.6ng/ml determined by ELISA. |
|
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Human IL-1 Rrp2 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%. |
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The purity of Human IL-1 Rrp2 is greater than 95% as determined by SEC-HPLC. |
Other Available Proteins:
Finding available proteins...
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