Human IL-12 R beta 1/CD212 Protein (ILR-HM212)

  • Express System: HEK293
  • Product Tag: C-hFc
  • Purity: > 95% as determined by Tris-Bis PAGE
  • Activity: Immobilized Human IL-12B, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-12 R beta 1, hFc Tag with the EC50 of 0.26ug/ml determined by ELISA. See testing image for detail.
  • Exact Sequence: Cys24-Glu540

Catalog: ILR-HM212

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Product Description Recombinant Human IL-12 R beta 1/CD212 Protein is expressed from HEK293 with hFc tag at the C-terminus.It contains Cys24-Glu540.

Product Background

Human IL12RB1 is an autosomal gene that is essential for mycobacterial disease resistance and T cell differentiation. Lung and T cell IL12RB1 expression is allele-biased, and the extent to which cells express one IL12RB1 allele is unaffected by activation. Furthermore following its expression the IL12RB1 pre-mRNA is processed into either IL12RB1 Isoform 1 (IL12Rβ1, a positive regulator of IL12 responsiveness) or IL12RB1 Isoform 2 (a protein of heretofore unknown function).

Product Category

Recombinant Protein

Target

IL-12 R beta 1/CD212

Gene/Protein ID

P42701-1

Species

Human

Exact Sequence

Cys24-Glu540
Molecular Weight The protein has a predicted MW of 83.85 kDa. Due to glycosylation, the protein migrates to 95-115 kDa based on Tris-Bis PAGE result.

Activity

Immobilized Human IL-12B, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-12 R beta 1, hFc Tag with the EC50 of 0.26ug/ml determined by ELISA. See testing image for detail.

Product Tag

C-hFc

Express System

HEK293
Purity > 95% as determined by Tris-Bis PAGE
Endotoxin Less than 1EU per ug by the LAL method.
Form Liquid
Shipping Shipped with dry ice.
Formulation Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage Valid for 12 months from date of receipt when stored at -80°C.; Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.
Immobilized Human IL-12B, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-12 R beta 1, hFc Tag with the EC50 of 0.26ug/ml determined by ELISA.
Human IL-12 R beta 1 on Tris-Bis PAGE under reduced condition. The purity is greater than 95%.

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