Name: Human IL-13 Protein (IL1-HM113)
Brand: KactusBio
SKU: IL1-HM113-100UG
Price: 375.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-13, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Avi Tag with the EC50 of 37.7ng/ml determined by ELISA. The affinity constant of 24.64 nM as determined in SPR assay (Biacore T200).
Amino Acid Range: Gly21-Asn132

Catalog #IL1-HM113

Size

100UG

500UG

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Human IL-13 Protein (IL1-HM113) Summary

Product Description	Recombinant Human IL-13 Protein is expressed from HEK293 with His tag at the C-terminus.It contains Gly21-Asn132.
Product Background	Interleukin-13 (IL-13) is a monomeric 17 kDa immunoregulatory cytokine that plays a key role in the pathogenesis of allergy, cancer, and tissue fibrosis. It is secreted by several helper T cell subsets, NK cells, mast cells, eosinophils, basophils, and visceral smooth muscle cells. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses. Positively regulates IL31RA expression in macrophages (By similarity).
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human IL-13 Protein (IL1-HM113) Specifications/Details

Protein	IL-13
Synonyms	IL13; IL-13; interleukin 13; NC30; P600; ALRH; BHR1; MGC116786; MGC116788; MGC116789
Accession	AAK53823
Species	Human
Biotinylated	no
Amino Acid Range	Gly21-Asn132
Molecular Weight	The protein has a predicted MW of 13.95 kDa. Due to glycosylation, the protein migrates to 35-50 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-13, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Avi Tag with the EC50 of 37.7ng/ml determined by ELISA. The affinity constant of 24.64 nM as determined in SPR assay (Biacore T200).
Product Tag	C-His
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 0.1 EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22 um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-13Ra1, hFc Tag captured on CM5 Chip via Protein A can bind Human IL-13, His Tag with an affinity constant of 24.64 nM as determined in SPR assay (Biacore T200).
	Immobilized Human IL-13, His Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-13Ra2, His Avi Tag with the EC50 of 37.7ng/ml determined by ELISA.
	Human IL-13 on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	Loaded Human IL-13, His Tag on Anti-His-Biosensor can bind Human IL-13Ra1, hFc Tag with an affinity constant of 40.70 nM as determined in BLI assay .
	The purity of Human IL-13 is greater than 95% as determined by SEC-HPLC.

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