Human IL-17B Protein (IL7-HM27B)

Immobilized Human IL-17B, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-17B Antibody, hFc Tag with the EC50 of 20.7ng/ml determined by ELISA (QC Test).

Human IL-17B on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-17B is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-17B, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-17B Antibody, hFc Tag with the EC50 of 20.7ng/ml determined by ELISA (QC Test).
Amino Acid Range: Gln21-Phe180

Catalog #IL7-HM27B

Price

$379⁵⁰

Size

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Human IL-17B Protein (IL7-HM27B) Summary

Product Description

Recombinant Human IL-17B Protein is expressed from HEK293 with hFc (IgG1) tag at the C-Terminus.It contains Gln21-Phe180.

Product Background

IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. IL-17B/IL-17RB expression patterns and biological activities in cancer and highlight issues that remain to be addressed to better characterize IL-17B and its receptor as potential targets for enhancing the effectiveness of the existing cancer therapies.

Human IL-17B Protein (IL7-HM27B) Specifications/Details

Protein	IL-17B
Synonyms	IL17B; Interleukin-17B
Accession	Q9UHF5
Species	Human
Biotinylated	no
Amino Acid Range	Gln21-Phe180
Molecular Weight	The protein has a predicted MW of 44.91 kDa. Due to glycosylation, the protein migrates to 50-60 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-17B, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-17B Antibody, hFc Tag with the EC50 of 20.7ng/ml determined by ELISA (QC Test).
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Shipping, Reconstitution, & Storage

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Dissolve the lyophilized protein in distilled water. It is recommended to resuspend at 0.5 mg/mL if the lyophilized powder is 100 ug or less, at 1mg/ml for 500ug or 1mg lyophilized powder. Do not mix by vortex or vigorous shaking.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

Validation Images

	Immobilized Human IL-17B, hFc Tag at 1ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Anti-IL-17B Antibody, hFc Tag with the EC50 of 20.7ng/ml determined by ELISA (QC Test).
	Human IL-17B on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-17B is greater than 95% as determined by SEC-HPLC.