Name: Human IL-17R alpha/CD217 Protein (CD7-HM1RA)
Brand: KactusBio
SKU: CD7-HM1RA-100UG
Price: 231.0 USD
Availability: InStock

Human IL-17R alpha/CD217 Protein (CD7-HM1RA)

Human IL-17R alpha, His Tag immobilized on CM5 Chip can bind Human IL-17A, His Tag with an affinity constant of 1.57 nM as determined in SPR assay (Biacore T200).

Immobilized Human IL-17R alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.44ug/ml determined by ELISA (QC Test).

Human IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.

The purity of Human IL-17R alpha is greater than 95% as determined by SEC-HPLC.

Express System: HEK293
Product Tag: C-His
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-17R alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.44ug/ml determined by ELISA (QC Test). The affinity constant of 1.57 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Amino Acid Range: Leu33-Trp320

Catalog #CD7-HM1RA

Size

100UG

500UG

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Product Description	Recombinant Human IL-17R alpha/CD217 Protein is expressed from HEK293 with His tag at the C-Terminus.It contains Leu33-Trp320.
Product Background	Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restricted to activated T cells, the IL‑17 R mRNA exhibits a broad tissue distribution, and has been detected in virtually all cells and tissues tested. The human IL‑17 R gene was localized to chromosome 22.
Product Category	Recombinant Protein / Antibody discovery

Protein	IL-17R alpha/CD217
Synonyms	CD217; CDw217; IL-17RA; IL17R; CANDF5; IL-17R; IL-17R-alpha; IL17Rα
Accession	Q96F46-1
Species	Human
Biotinylated	no
Amino Acid Range	Leu33-Trp320
Molecular Weight	The protein has a predicted MW of 34.6 kDa. Due to glycosylation, the protein migrates to 60-70 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-17R alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.44ug/ml determined by ELISA (QC Test). The affinity constant of 1.57 nM as determined in SPR assay (Biacore T200). See testing image for detail.
Product Tag	C-His
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1EU per ug by the LAL method.

Form	Lyophilized
Shipping	Shipped at ambient temperature.
Formulation	Lyophilized from 0.22um filtered solution in PBS (pH 7.4). Normally 8% trehalose is added as protectant before lyophilization.
Reconstitution	Centrifuge the tube before opening. Reconstituting to a concentration more than 100 ug/ml is recommended. Dissolve the lyophilized protein in distilled water.
Stability And Storage	-20 to -80°C for 12 months as supplied from date of receipt.；-80°C for 3 months after reconstitution.；Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Human IL-17R alpha, His Tag immobilized on CM5 Chip can bind Human IL-17A, His Tag with an affinity constant of 1.57 nM as determined in SPR assay (Biacore T200).
	Immobilized Human IL-17R alpha, His Tag at 5ug/ml (100ul/well) on the plate. Dose response curve for Biotinylated Human IL-17A, His Tag with the EC50 of 0.44ug/ml determined by ELISA (QC Test).
	Human IL-17R alpha on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-17R alpha is greater than 95% as determined by SEC-HPLC.