Name: Human IL-17RB Protein (IL1-HM2RB)
Brand: KactusBio
SKU: IL1-HM2RB-100UG
Price: 330.0 USD
Availability: InStock

Express System: HEK293
Product Tag: C-hFc (IgG1)
Purity: > 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Activity: Immobilized Human IL-25, His Tag (Cat.IL2-HM125) at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RB, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA.
Amino Acid Range: Arg18-Per292

Catalog #IL1-HM2RB

Size

100UG

500UG

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Human IL-17RB Protein (IL1-HM2RB) Summary

Product Description	Recombinant Human IL-17RB Protein is expressed from HEK293 with hFc (IgG1) tag at the C-terminus.It contains Arg18-Per292.
Product Background	Among inflammatory mediators, a growing body of evidence emphasizes the contribution of the interleukin 17 (IL-17) cytokine family in malignant diseases. Besides IL-17A, the prototypic member of the IL-17 family, several experimental findings strongly support the role of the IL-17B/IL-17 receptor B (IL-17RB) pathway in tumorigenesis and resistance to anticancer therapies. In mouse models, IL-17B signaling through IL-17RB directly promotes cancer cell survival, proliferation, and migration, and induces resistance to conventional chemotherapeutic agents.
Product Category	Recombinant Protein / Antibody discovery / Antibody discovery/Others

Human IL-17RB Protein (IL1-HM2RB) Specifications/Details

Protein	IL-17RB
Synonyms	IL-17 receptor B; IL-17RB; IL-17ER; Evi27; IL-17 RH1; IL-17ER; IL17RB
Accession	Q9NRM6-1
Species	Human
Biotinylated	no
Amino Acid Range	Arg18-Per292
Molecular Weight	The protein has a predicted MW of 56.24 kDa. Due to glycosylation, the protein migrates to 70-90 kDa based on Bis-Tris PAGE result.
Activity	Immobilized Human IL-25, His Tag (Cat.IL2-HM125) at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RB, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA.
Product Tag	C-hFc (IgG1)
Fluorophore	Unconjugated
Expression System	HEK293
Purity	> 95% as determined by Bis-Tris PAGE;> 95% as determined by HPLC
Endotoxin	Less than 1 EU per ug by the LAL method.

Form	Liquid
Shipping	Shipped with dry ice.
Formulation	Supplied as 0.22 um filtered solution in PBS (pH 7.4).
Stability And Storage	Valid for 12 months from date of receipt when stored at -80°C.； Recommend to aliquot the protein into smaller quantities for optimal storage. Please minimize freeze-thaw cycles.

	Immobilized Human IL-25, His Tag (Cat.IL2-HM125) at 1ug/ml (100ul/well) on the plate. Dose response curve for Human IL-17RB, hFc Tag with the EC50 of 6.2ng/ml determined by ELISA.
	Human IL-17RB on Bis-Tris PAGE under reduced condition. The purity is greater than 95%.
	The purity of Human IL-17RB is greater than 95% as determined by SEC-HPLC.

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